Role of Natural Products in Drug Discovery part 2 скачать в хорошем качестве

Role of Natural Products in Drug Discovery part 2

Role of Natural Products in Drug Discovery & Development (Part 2) | Week 3 · Day 1 Bharat Technology — Department of Pharmacognosy 🌿 Welcome back! In today’s lecture (Lecture 5) we continue our deep dive into how natural products contribute to modern drug discovery. This session covers target identification and validation, how drugs interact with biological targets (enzymes, GPCRs, ion channels, intracellular receptors), and practical considerations in turning a lead compound into an oral drug candidate. What you’ll learn • Lipinski’s Rule of Five and its relevance for oral drugs • The drug discovery → preclinical → clinical → approval pipeline • Major drug targets and mechanisms of action (enzymes, GPCRs, ion channels, tyrosine kinases, intracellular receptors) • Target identification tools (microarrays, radioligands, ESTs, in silico methods) • Target validation approaches and why they matter for successful development Who this is for Undergraduate & postgraduate pharmacy students, researchers, and anyone interested in natural products and drug discovery.