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his week’s weigh-in comes from New York City, where Christopher and Laraine Durham share an update on life in maintenance and what it looks like to stay consistent after significant weight loss with GLP-1 medications. Laraine reflects on maintaining her weight loss nearly two years after reaching her goal, while Christopher talks about remaining steady on his dose after losing more than 100 pounds since beginning GLP-1 treatment in September 2023. As always, the second half of the episode focuses on viewer questions. This week’s conversation covers some of the most common and misunderstood topics in the GLP-1 space, including: Why some patients still pay full price for GLP-1 medications Whether a higher-dose pen can be used at a lower dose The difference between compounded medications and generics Reports of phantom smells and other unusual sensory changes What happens when someone reaches the maximum dose How dosing units work with compounded medication Whether there can be a temporary lull when titrating up Changes in taste and food satisfaction Adjusting mentally after major weight loss Looking beyond the scale to measure progress Christopher and Laraine speak from their own experience as patients who have collectively lost more than 150 pounds using tirzepatide, Mounjaro, and Zepbound. Their goal is to help others better understand the realities of treating the disease of obesity with GLP-1 medications. Viewers are encouraged to leave questions in the comments for future episodes. +++++++++++++++++++++++++++++++++++++++ Get your Hume BodyPod today and use our exclusive Downsized code for up to 50% total savings! 👉 Use our Code: THEDOWNSIZED Link to purchase: https://humehealth.com//discount/THED... Start your weight loss journey today! We use Mochi Health: https://app.joinmochi.com/eligibility... Use Laraine’s code for $40 off: QIYGO8. Me Again Iphone GLP-1 App: https://apps.apple.com/us/app/meagain... AMAZON GLP-1 Companion Product Store: https://www.amazon.com/shop/downsized As an Amazon Associate, I earn from qualifying purchases. DOWNSIZED LINKS Website: https://thedownsized.org Be our guest on The Downsized Dish: apply at https://thedownsized.org/downsized-dish/ Https://Thedownsized.Org/ Book The Downsized At Sea Cruise 2026: Https://Thedownsized.Org/Downsized-At... FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ +++++++++++++++++++++++++++++++++++++++ 00:00 What Happens If You Max Out Your GLP-1 Dose? Weekly Weigh-In 02:57 Weekly Weigh-In 03:18 Laraine's Weigh In 07:06 Christopher's Weigh-In 14:39 Weekly Weigh-In Q&A 15:13 Where can I find tirzepatide or Mounjaro for less than $399 a month? 17:08 Why would anyone still pay thousands per month for GLP-1 meds? 20:34 Are there GLP-1 companies to avoid? Is ARC legit? 22:16 What maintenance dose are you each using? 27:36 What’s the difference between tirzepatide, Mounjaro, Zepbound, Wegovy, Ozempic, and semaglutide? 31:36 How do syringe units work with compounded doses? 34:02 Why isn’t compounded medication considered a generic? 36:55 Can GLP-1s cause phantom smells like burnt toast? 38:15 Can a higher-dose pen be used at a lower dose to make it last longer? 38:56 What happens if you max out dosing but still want more weight loss? 39:55 Did you lose 40% of your body weight? 43:00 How do you adjust mentally to your new body and wardrobe? 47:45 Is there a lull when you titrate up to a higher dose? 48:45 Does food start to taste metallic or different on GLP-1s? 50:04 How do you focus on progress beyond the scale? 52:31 How do you cook for protein without relying on shakes?