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#alkylatingagents #antitumor #chemotherapy Mechanism of Aklyating Agents: 1. Alkylating agents are a class of chemotherapy drugs that work by adding an alkyl group to DNA, which leads to damage in the DNA strands. 2. The addition of the alkyl group causes the DNA strands to cross-link, preventing DNA replication and ultimately leading to cell death. 3. Alkylating agents can target cancer cells at various stages of the cell cycle, making them effective against rapidly dividing cells. 4. Some examples of alkylating agents used in chemotherapy include cyclophosphamide, cisplatin, and temozolomide. 5. Alkylating agents can also cause damage to healthy cells in the body, leading to side effects such as nausea, vomiting, hair loss, and increased risk of infections. ----------------------------------------------------------------------------------------------------- Mechanism of Action of Anti-tumour Antibiotics: 1. Anti-tumor antibiotics are a class of chemotherapy drugs that work by blocking the enzymes necessary for DNA replication and cell division. 2. These drugs bind to DNA and interfere with its replication, leading to DNA damage and cell death. 3. Anti-tumor antibiotics are typically used to treat solid tumors such as breast cancer, lung cancer, and ovarian cancer. 4. Some examples of anti-tumor antibiotics include doxorubicin, daunorubicin, and bleomycin. 5. Side effects of anti-tumor antibiotics can include nausea, vomiting, hair loss, increased risk of infections, and damage to the heart or lungs. Anti-cancer drugs can be classified into different categories based on their mechanism of action, such as alkylating agents, antimetabolites, topoisomerase inhibitors, and monoclonal antibodies. ------------------------------------------------------------------------------------------------------------ Alkylating agents work by adding an alkyl group to DNA, leading to DNA damage and preventing the cancer cells from dividing and growing. Antimetabolites mimic the structure of essential molecules, such as nucleotides, needed for DNA synthesis and cell division, and interfere with cancer cell growth and replication. Topoisomerase inhibitors target enzymes called topoisomerases, which are important for DNA replication and repair, and prevent cancer cells from dividing and growing. Monoclonal antibodies are engineered proteins that recognize and target specific proteins or receptors on cancer cells, leading to their destruction or slowing their growth. Some monoclonal antibodies can also stimulate the immune system to attack cancer cells. There are many different types of anti-cancer drugs, and each type targets cancer cells in a different way. Here are some examples of commonly used anti-cancer drugs: Alkylating agents: Cyclophosphamide, Carmustine, and Busulfan. Antimetabolites: Methotrexate, Fluorouracil, and Gemcitabine. Topoisomerase inhibitors: Irinotecan, Topotecan, and Etoposide. Mitotic inhibitors: Paclitaxel, Docetaxel, and Vinblastine. Hormone therapy drugs: Tamoxifen, Letrozole, and Anastrozole. Immunotherapy drugs: Pembrolizumab, Nivolumab, and Ipilimumab. Targeted therapy drugs: Trastuzumab, Imatinib, and Bevacizumab. It's important to note that this is not an exhaustive list, and there are many other anti-cancer drugs available, each with their own specific uses and side effects. It's also worth noting that cancer treatment is highly personalized and may involve a combination of different drugs and treatments depending on the type and stage of cancer. Chemotherapy drugs work by targeting rapidly dividing cells, which are characteristic of cancer cells. These drugs interfere with the ability of cancer cells to divide and grow, leading to cell death. Chemotherapy drugs can target cancer cells in various stages of the cell cycle, including the resting phase (G0), DNA synthesis (S phase), mitosis (M phase), and other phases of the cell cycle. Some chemotherapy drugs work by damaging the DNA in cancer cells, preventing them from dividing and replicating. Other chemotherapy drugs target specific proteins or enzymes in cancer cells that are critical for their survival and growth, leading to their death or slowing their growth. list of chemotherapy drugs types of chemotherapy drugs chemotherapy drugs classification chemotherapy drugs side effects oral chemotherapy drugs list list of strongest chemo drugs chemotherapy drugs for breast cancer chemotherapy drugs price