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Quantitative Antigen Detection Using Fluorescence Quenching Competitive Immunoassay

NE_2014_12 Malaria is a disease of unfortunate notoriety that shares symptoms with many common ailments. This is a particularly problematic issue in less privileged countries, since the available diagnostic tests not reliant upon specialized equipment and expertise can be unreliable and qualitative. This project strives to address this predicament by developing a simple, accurate test that takes advantage of the properties of gold nanoparticles, using them in a fluorescence quenching competitive immunoassay system. When a sample containing the analyte is introduced to the system, it will fluoresce with intensity corresponding to the concentration, allowing for quantitative diagnosis.