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06/16/2025 - Hi-Risk/Recurrent/Advanced PCa Men & Caregivers
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06/16/2025 - Hi-Risk/Recurrent/Advanced PCa Men & Caregivers

AnCan is grateful to the following sponsors for making this recording possible: Bayer, Novartis, Johnson and Johnson, Myriad Genetics, Telix, Blue Earth Diagnostics and Foundation Medicine AnCan respectfully notes that it does not accept sponsored promotion. Any drugs, protocols or devices recommended in our discussions are based solely on anecdotal peer experience or clinical evidence. AnCan cannot and does not provide medical advice. We encourage you to discuss anything you hear in our sessions with your own medical team. AnCan reminds all Participants that Adverse Events experienced from prescribed drugs or protocols should be reported to the pharmaceutical manufacturer or the FDA Adverse Event Reporting System (FAERS). To do so call 1-800-332-1066 or download interactive FDA Form 3500 https://www.fda.gov/media/76299/download All AnCan’s groups are free and drop-in … join us in person sometime! You can find out more about our 12 monthly prostate cancer meetings at https://ancan.org/prostate-cancer/ Sign up to receive a weekly Reminder/Newsletter for this Group or others at https://ancan.org/contact-us/ Join our other free and drop in groups: Men (Only) Speaking Freely…1st & 3rd Thursdays @ 8.00 pm Eastern https://ancan.org/men-speaking-freely/ Veterans Healthcare Navigation… 1st & 3rd Tuesdays @ 8.00 pm Eastern Schmier Room https://ancan.org/veterans/ Veterans Speaking freely... 4th Tuesday @ @ 8.00 pm Eastern Schmier Room Editor's Pick: After 20 years continuously on AS, 3+3 becomes metastatic (rd) Topics Discussed After 20 years continuously on AS, 3+3 becomes metastatic; man with recurrence must learn to be his own best advocate; denovo Mx Alaskan needs better treatment fromf the VA; success report from PBRT; trust Dr. Zhao!; primary treatment with BPH; long term management of recurrent, oligo-Mx disease; abo vs daro; infections and A-fib defer PrCa Tx.; scans show clean but HT causes sweats and fatigue; youngr Gent shows nothing on PSMA at 0.14 - needs to switch his care; HT is doing its job Chat Log steve cavill - Melbourne, Australia sent: 5:32 PM what pirads? That gives a good idea of grade hmm ok, biopsy would be useful ! Bob Alvord sent: 6:02 PM I download all my scans, biopsy reports and labs to Chat Gtp. Chat returns detailed interpretations after I also mention that I am not a doctor, so in plain language. I also ask Chat for relevant questions. Not a perfect way but a good way to generate questions. Jim Marshall, Alexandria, VA sent: 6:08 PM Veterans Support Group, Tuesday at 2000ET. Jim Marshall, USAF(Ret) Jim Marshall, Alexandria, VA sent: 6:35 PM If one takes FINASTERIDE it will artifically drop the PSA by 50%. Russ - PCaWarrior sent: 6:50 PM NCCN Low/favorable IR: SBRT alone is acceptable; ADT is optional. Unfavorable IR: SBRT + 4–6 months ADT is recommended. High risk: SBRT + 2–3 years ADT (Category 2A). Very high risk: SBRT only in trial settings; standard is EBRT ± brachytherapy + long‑term ADT. Finasteride : PSA. Finasteride blocks 5AR type 2. That is the predominant type in the prostate and PCa cells. DHT drops. PSA drops. Androgens (e.g. T) upgregulate PSA. ARSIs (e.g. Xtandi) downregulate it. Practical solution to upregulating or downregulating is to measure PSA in the same environment. Jim Marshall, Alexandria, VA sent: 6:56 PM Was on Eligard + ABI for 5 years and NO SWEAT with side effects and now 3 years into Treatment Holiday and counting.. Mitigated ADT + ABI with exercise every day and diet. Jim Marshall Richrd - Virginia sent: 7:04 PM i have to leave. I will talk next week. dan, alexandria sent: 7:06 PM Thanks all... I have to leave. Alain sent: 7:07 PM thank you all! Russ - PCaWarrior sent: 7:09 PM https://pubmed.ncbi.nlm.nih.gov/33293... Actinium is pretty bad for salivary AEs. Ben Nathanson sent: 7:10 PM It's less of an issue with an ADC Russ - PCaWarrior sent: 7:11 PM what trial is it? Gary sent: 7:12 PM I have to leave. See you next time. Ben Nathanson sent: 7:12 PM NCT06402331 steve cavill - Melbourne, Australia sent: 7:15 PM bye all, i have to leave also John G. sent: 7:15 PM https://meds.is/en/comparison/darolut... https://www.renalandurologynews.com/r... AnCan Barniskis Room sent: 7:22 PM Depo-Provera; tofu Bob Alvord sent: 7:33 PM Thank you all! See you next week! AnCan Barniskis Room sent: 7:34 PM https://www.dukehealth.org/find-docto... Hannah McManus Ben Nathanson sent: 7:36 PM John G --The first of these doesn't seem to cite any sources, meaning none of the claims can be verified by readers. I distrust that. The second is in the context of chemotherapy, and is also retrospective -- not clear it's relevant to your case. Also fwiw the work was funded by Bayer, the maker of daro. Steven T sent: 7:45 PM Thanks everyone! AnCan Barniskis Room sent: 7:45 PM 877 582 7011 GoTo Support

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