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Ankylosing spondylitis is an inflammatory disease that, over time, can cause some of the bones in the spine (vertebrae) to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply. Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body. "Ankylosis" means fused bones or other hard tissue. "Spondylitis" means inflammation in your spinal bones, or vertebrae. Severe cases can leave your spine hunched. There’s no cure for AS. But medication and exercise can ease pain and help keep your back strong.. AS often starts in your sacroiliac joints, where your spine connects to your pelvis. It can affect places where your tendons and ligaments attach to bones. It can even cause your vertebrae to fuse together. You might have pain or stiffness in your: Lower back Buttocks Shoulders Hands Rib cage Hips Thighs Feet Heels You might notice: Pain that’s worse in the morning or after sitting for a long time A rigid spine that curves forward Tiredness Swelling in your joints Trouble taking deep breaths Symptoms can differ from person to person. Your condition also may change quicker or slower than someone else’s. Ankylosing Spondylitis Causes Researchers aren’t sure what triggers AS, but they think it’s tied to your genes. Most people with AS have a gene that makes a protein called HLA-B27. Doctors think it tells your immune system to attack some common bacteria in your body and sets off AS symptoms. Ankylosing Spondylitis Risk Factors Certain things that you can’t control might raise your risk of AS: Sex. Men are more likely than women to have AS, and it strikes them earlier and harder. Women tend to have a milder form of AS called non-radiographic axial spondyloarthritis. Age. AS often starts in your teens and young adulthood. About 80% of cases begin before the person turns 30, and 95% by age 45. Ankylosing Spondylitis Diagnosis AS can be tough to spot because so many people have back pain, its main symptom. A diagnosis may be even trickier for women because the condition is much more common in men. There’s also no single test to confirm AS. Your doctor may rely on your symptoms, a physical exam, and blood tests. You also might have an X-ray or an MRI. But this doesn’t always help, because joint damage may not show up right away on imaging tests. Hip replacement in ankylosing is technically demanding procedure and will give excellent resulta if proper technique is followed. Usually both sides of hip are involved. Fracture and ortho clinic 4274/2 1st phase Girinagar, Banashankari 3rd Stage, Banashankari, Bengaluru, Karnataka 560085 For appointments; +91 8197055044 drsharath.com