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In this compelling episode of Voices of Otolaryngology, host Rahul Shah, MD, MBA, talks with G. Lee Bryant, Jr., MD, a veteran private practice otolaryngologist based in Nashville and an innovator in in-office procedures. Dr. Bryant recounts his extraordinary personal journey as a melanoma survivor, including the self-biopsy that saved his life, and how that experience reshaped his approach to patient care. Beyond his survival story, Dr. Bryant shares how he and his colleagues pioneered in-office rhinology and sinus surgery techniques. He explains the clinical, economic, and patient-centered benefits of shifting appropriate surgeries from the hospital to the office, while emphasizing safety, team-based care, and ongoing education for the next generation of ENT specialists. Listeners will gain insights into the evolution of minimally invasive otolaryngology, strategies for building successful office-based surgical programs, and Dr. Bryant’s perspective on why this movement represents the future of patient care. Timestamps: 00:12 – Introduction to Dr. G. Lee Bryant Jr. at the 2025 OTO Forum 01:16 – Dr. Bryant’s Nashville roots, career path, and decades in private practice 01:53 – His personal story as a melanoma survivor and how he self-biopsied his thumb 04:07 – How cancer changed his outlook and deepened his patient relationships 05:44 – Lessons on vigilance: the importance of re-biopsy when things don’t add up 06:41 – Overview of Dr. Bryant’s weekly schedule: clinic, OR, and office surgery 07:55 – The history of his group practice and partnership with Dr. Scott Fortune 08:52 – How he and his team pioneered office-based turbinate reduction and rhinology 09:30 – Why in-office procedures often have less bleeding and faster recovery 11:10 – Techniques for local anesthesia and the evolution of balloon dilation 12:17 – The setup of a successful office surgical suite, from image guidance to staff roles 13:55 – Transitioning septoplasty and functional endoscopic sinus surgery to the office 15:05 – Expanding office surgery beyond rhinology: laryngeal, TMJ, and ear procedures 16:14 – Economic and patient benefits of office-based care in high-deductible environments 17:26 – How awake patients tolerate procedures—and why outcomes can be superior 18:35 – New frontiers: nasal valve interventions, posterior nasal nerve ablation, and more 19:30 – Eustachian tube dilation and other disease states now managed in-office 21:23 – Safety protocols, team training, and lessons from complications 24:55 – Why awake feedback and image guidance enhance procedural safety 26:12 – Memorable patient outcomes and the satisfaction of immediate results 28:02 – The evolution of balloon dilation and its role in functional outcomes 30:21 – Audience questions on costs, anesthesia approaches, and training pathways 31:28 – Why in-office surgery requires team infrastructure and ongoing education 33:22 – Trends: 75% of private practices now performing some office-based procedures 35:13 – Targeted septoplasty and shifting treatment algorithms for patient selection 37:03 – Dr. Bryant’s outlook on the future of minimally invasive ENT and private practice 39:03 – Reflections on professional satisfaction, patient relationships, and mentorship Mentioned Resources: Bryant’s Blog: https://drleebryant.com/ AAO-HNSF Private Practice Section (OPPS): https://www.entnet.org/ Otolaryngology Clinics of North America (In-Office Surgery Guide): https://www.oto.theclinics.com/ Inspire: https://fortherest.inspiresleep.com/