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“Smart Devices and Systems for Surgical Guidance—Augmenting Today’s Surgeon.” Jones Seminars on Science, Technology, and Society. Ryan Halter, Assistant Professor, Thayer School of Engineering March 1, 2019 Over 48 million surgical procedures are performed each year in the US. While new approaches and surgical technologies have enabled surgeons to excel in achieving functional outcomes of surgical procedures being performed the focus has shifted to improving post-surgical quality of life, decreasing the rates of recurrences, and reducing the overall cost to the healthcare system. Our lab has been developing several smart surgical devices with the aim of augmenting a surgeon’s perception to enable them to achieve these improved outcomes. Our focus has been on developing technologies that sense and image the electrical properties of tissue for surgical guidance and on developing image-guidance-based surgical navigation platforms. We will present several case studies of technologies being developed in our lab to meet clinical needs ranging from traumatic brain injury monitoring to surgical guidance during prostate cancer procedures and oral cavity and throat-based surgeries. In all these applications, we focus on the challenges currently facing surgeons and take a surgeon and patient-centered design process to develop technologies that fit within the operating space.