Clean Air & Gas Valve Applications in the Biopharm Industry - A Webinar by Karl Lutkewitte скачать в хорошем качестве

Clean Air & Gas Valve Applications in the Biopharm Industry - A Webinar by Karl Lutkewitte

In this webinar, a seasoned valve industry professional covers everything you need to know about selecting, installing, and commissioning pressure reducing valves (PRVs) for clean air and gas applications in upstream cell culture. The session focuses on two critical areas: the incubator suite and the bioreactor suite. The presentation begins with incubator applications, where O2, CO2, and clean compressed air are supplied through wall panels and regulated down to working pressures. You'll learn which valve models are best suited for these low-flow, low-pressure environments and why. From there, the webinar moves into bioreactor applications — both stainless steel and single-use systems. Topics include gas sparging, sterile vent filtration, back pressure regulation, single-use bag inflation, and precision CO2 flow control using Equilibar FD and SD valves. Real-world installation photos from facilities across North America bring the concepts to life. Key technical fundamentals covered include: How pressure reducing valves work as mechanical force balance devices Droop (set point offset) and how to minimize it through spring selection and higher inlet pressures Seat leakage, deadheading risks, and why you must close inlet ball valves after filling to pressure Lockup and how softer seat materials (EPDM, Teflon) reduce it Self-relieving valves and when to specify captured vent options for hazardous gases The session also addresses common system design questions: whether a primary PRV is needed upstream (usually no — higher inlet pressure improves performance), how many points of use one regulator can serve, and installation orientation for gas vs. liquid service. One of the most valuable segments covers commissioning best practices. The presenter shares why you should never blow lines down through installed regulators — they collect welding debris, cutting chips, and contaminants that damage soft seats and tiny orifices. Remove the regulator first and install a spool piece instead. The webinar wraps up with two final valve options: air augmentation for remote setpoint control and droop reduction via PLC or I/P transducer, and factory-installed gauge ports that eliminate the need for separate diaphragm seal gauges. Whether you're an engineer, system integrator, or facility designer in biopharma, cell therapy, gene therapy, or vaccine manufacturing, this session is packed with practical, field-tested advice.