Lowering Triglycerides with omega-3 FA? Dr. Nissen (Cleveland) скачать в хорошем качестве

Lowering Triglycerides with omega-3 FA? Dr. Nissen (Cleveland)

⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ WEITERE INFOS UND LINKS ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ ⇓ Dr. Steven Nissen, who has initiated numerous pivotal cardiovascular outcome trials, analyses his approach to the treatment of hypertriglyceridemia, discussing the divergent results from the STRENGTH and REDUCE-IT studies, which both compared high dosage omega-3 fatty acids in people with cardiovascular risk and moderately elevated triglycerides. Articles discussed: Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk The STRENGTH Randomized Clinical Trial SJ Nicholls et al., JAMA 2020 https://jamanetwork.com/journals/jama... Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia (REDUCE IT) DL Bhatt et al., NEJM 2019 https://www.nejm.org/doi/full/10.1056... Risk of Cardiovascular Events Associated With Selective COX-2 Inhibitors D Mukherjee et al., JAMA 2001 https://jamanetwork.com/journals/jama... Effect of Muraglitazar on Death and Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes Mellitus SE Nissen et al., JAMA 2005 https://jamanetwork.com/journals/jama... Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes SE Nissen and K Wolski, NEJM 2007 https://www.nejm.org/doi/10.1056/NEJM... Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis M Yokoyama et al., Lancet 2007 https://www.thelancet.com/article/S01... Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: a prospective, placebo-controlled randomized trial (EVAPORATE): interim results MJ Budoff et al., Cardiovascular Research 2021 https://academic.oup.com/cardiovascre... Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease (CANTOS) PM Ridker et al., NEJM 2017 https://www.nejm.org/doi/full/10.1056... FDA ADVISORY COMMITTEE BRIEFING DOCUMENT 2019 https://www.fda.gov/media/132479/down... Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk A Secondary Analysis of the STRENGTH Trial SE Nissen et al., JAMA Cardiology 2021 https://jamanetwork.com/journals/jama... Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes CP Cannon et al., NEJM 2015 https://www.nejm.org/doi/10.1056/NEJM... 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk Mach et al. https://academic.oup.com/eurheartj/ar...