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Presented by Playground Global at SF Deep Tech Week 2025 (https://luma.com/dtw2025-playground) https://www.playground.vc/ Deep Tech Week is a decentralized conference hosting the worlds best entrepreneurs and investors bringing science fiction technologies to life https://www.deep-tech-week.com/ ~~~~~~~~~ A rapid tour of Playground Global’s deep-tech thesis—from million-qubit quantum data centers to particle-accelerator lithography, muon sensing, AI-native chips, superconducting compute, faster photosynthesis, RNA structure prediction, and quantum MRI. Playground Global kicks off Deep Tech Week (San Francisco) with a clear thesis: we back the tiny subset of “improbable” startups that solve hard scientific problems on investable timelines. The talk outlines focus areas—next-gen compute, quantum & AI; automation/robotics; infrastructure & energy transition; engineered life sciences—and the operator-heavy team behind the bets. Highlights include: Quantum computing: building data-center–style facilities in Australia & Illinois with racks, networking, and cryogenic plants targeting million-qubit systems. Advanced semiconductors: beyond EUV’s molten-tin plasma, a particle-accelerator–based light source aimed at next-gen lithography. Generative AI, re-architected: investments to break Von Neumann bottlenecks and make AI compute commercially scalable. Superconducting classical compute: post-transistor architectures (e.g., Josephson junctions) promising ~10–100× energy cuts and ~100× speedups for classical workloads. Muon sensing: underground detectors turn cosmic-ray muons into 3D density maps for smarter, lower-impact mining. Enhanced photosynthesis: enzyme engineering to convert CO₂ + H₂O + photons into more sugars → higher yields. RNA structure prediction: precision models for RNA/protein interactions to enable targeted therapeutics. Quantum MRI contrast: hyperpolarized agents that make existing MRIs 100×+ more informative. The message: deep tech isn’t “decades away”—many breakthroughs are a handful of years out.