New approach for single-use clarification of biological solutions // Bettina Ledergerber скачать в хорошем качестве

New approach for single-use clarification of biological solutions // Bettina Ledergerber

Single-use solutions are becoming more and more relevant in more and more applications in the whole life-science industry. Thurne has been offering solutions for containment of potent and/or hazardous powders, filtration solutions, and handling of liquids for many years, and with this video, we want to give an up-to-date picture of our capabilities by having Filtrox presenting typical applications and solutions as well as describing some case studies as examples. Filtrox focuses on in-depth filtration, which means the removal of solid particles in the size of 0.1 to 10 microns, generally referred to as microfiltration. Typical microparticles are bacteria, yeast cells, cell fragments, or proteins. These particles are not visible to the human eye, but they make the liquid turbid so that one cannot see through. Through microfiltration, the liquid becomes clear. The video introduces the first depth filter system using the advantages of the alluvial (specifically cake or precoat) filtration technology in a single-use format. The filtration system that removes particles (e.g. cells, bacteria, yeast), impurities like HCP, DNA, and other turbid matter is highlighted in this video. The topic includes a system that is fully scalable and fulfills all validation requirements. The examples are provided of some typical applications such as CHO cell removal and bacterial removal and an explanation of practical handling and scale-up. Topics and technologies covered are included:  A new approach for single-use clarification of biological solutions. Reduce the clarification process from two steps to one by use of single-use alluvial filtration. Spokesperson: Bettina Ledergerber // Filtrox, Global Application Engineer www.filtrox.com www.thurne.se