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NF1 and Plexiform Neurofibroma (PN): Updates in Treatment and Clinical Trials This presentation provides a comprehensive overview of NF1-PN, including a review of the natural history of PN and warning signs of malignancy, a discussion of current treatment options, and updates on new and upcoming clinical trials and research studies. Presented at the 2025 CTF NF Summit by: Chelsea Kotch, MD, MSCE, Children's Hospital of Philadelphia 🔔 Subscribe & click the bell to stay informed and empowered: https://www.youtube.com/user/ctforg?s... About CTF: The Children’s Tumor Foundation (CTF) is the drug discovery engine for NF. Everything we do is to bring treatments to patients as we work toward a cure. By connecting patients, doctors, scientists, and pharma, we drive treatments, advance care, and deliver results for millions affected by neurofibromatosis or schwannomatosis, collectively referred to as NF. Our patient-first collaborative approach accelerates drug development and brings life-changing therapies to patients faster, driven by our mission to end NF. What is NF? NF refers to a group of genetic conditions that cause tumors to grow on nerves throughout the body. NF affects 1 in 2,000 births and may lead to blindness, deafness, bone abnormalities, disfigurement, learning disabilities, disabling pain, or cancer. NF affects all races, ethnic groups, and genders equally. The types of NF include neurofibromatosis type 1 (NF1) and all types of schwannomatosis (SWN), including NF2-related schwannomatosis (NF2-SWN), formerly called neurofibromatosis type 2 (NF2). Visit our website at https://www.ctf.org/ Donate today at https://www.ctf.org/ways-to-give/ Follow us on our social media platforms: Facebook - / childrenstumor Instagram - / childrenstumor X - / childrenstumor LinkedIn - / children's-tumor-foundation TikTok - / childrenstumor #endnf #nf1 #nf2 #nf2swn #swn #childrenstumor #neurofibromatosis #schwannomatosis #nervetumor #tumor