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Use of the femtosecond laser is enabling safe cataract surgery in difficult clinical situations, including eyes with white intumescent cataracts and those with zonular dialysis. Robert J. Cionni, MD, medical director, The Eye Institute of Utah, Salt Lake City, illustrated the use of a proprietary femtosecond laser (LenSx, Alcon Laboratories) in two challenging cases. One eye had a white mature cataract (as in the video shown here) and the second was a post-trauma case with marked zonular dialysis and a dense lens. The femtosecond laser was used in both cases to create the capsulotomy and corneal incisions, and it was used to perform lens fragmentation in the eye with zonular dialysis. The device could not be used with the white cataract, because the laser energy does not penetrate very deeply into the opaque lens material. However, its use for capsulotomy in the latter case was an advantage, Dr. Cionni noted. "Typically, when performing capsulotomy in eyes with white intumescent cataracts, the fear is that the increased intralenticular pressure will cause the capsule to splay out. Using the [femtosecond] laser to open the capsule, without ever opening the eye, allows the natural anterior chamber pressure to counteract the intralenticular pressure and results in a beautiful capsulotomy without any radial tears," Dr. Cionni explains.