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Diagnosis: Invasive left-sided rhino-cerebral mucormycosis History Four years ago, the patient presented with: • Chief complaints: Left-sided nasal blockage, facial swelling, and headache. • Risk factors: History of uncontrolled diabetes mellitus (if applicable). • Examination: Blackish necrotic tissue seen over the left middle meatus and palate, decreased sensation over left cheek, and mild proptosis. Management • Surgical intervention: I performed endoscopic sinus debridement along with partial left maxillectomy to achieve complete clearance of necrotic and infected tissue. • Medical management: Postoperative IV liposomal amphotericin B was given as per protocol. • Post-op care: Regular follow-up with nasal endoscopies and diabetes control. Follow-Up (After 4 Years) • The patient is absolutely asymptomatic. • Nasal endoscopy: Completely normal cavity with no evidence of recurrence. • Facial aesthetics: Maintained well with artificial dentures replacing the resected maxilla. • Quality of life: Fully restored, no complaints of nasal deformity or functional loss. Conclusion This case highlights the importance of early diagnosis, radical surgical clearance, and appropriate antifungal therapy in managing invasive rhino-cerebral mucormycosis. Long-term follow-up shows that timely, aggressive management can result in excellent functional and cosmetic outcomes even after extensive surgery.