Haplotypes and imputation | Introduction to genomics theory | Genomics101 (beginner-friendly) скачать в хорошем качестве

Haplotypes and imputation | Introduction to genomics theory | Genomics101 (beginner-friendly)

We continue the beginner-friendly lecture series introducing basic concepts in #genomics, with a focus on single nucleotide polymorphism (#SNP) data. In this part, we talk about the concept of haplotypes, including an optional short pen and paper exercise to identify haplotype combinations. As a follow-up, we talk about the basic theory behind the genomic #imputation including the possibilities behind it. The imputation of sporadically missing SNPs is explained, as well as imputation from lower to higher density SNP chips. Playlist with the full videos:    • Introduction to Genomics - course   All PowerPoint presentations are available at: https://github.com/GenomicsBootCamp/I... Parts of the video: 0:00 - Summary from previous lectures 0:48 - Haplotypes 5:07 - Phasing 7:16 - Imputation - general definition 8:22 - Imputation of sporadically missing genotypes 9:40 - Imputation between different SNP densities 13:12 - Imputation accuracy and practical use 17:28 - Summary of the lecture Image source in thumbnail: https://www.pexels.com/photo/starry-s... Support the channel ******************************************* To support the Genomics Boot Camp channel, check out the associated site for genotyping services covering companion animals, livestock and more: https://azdatasolutions.eu/