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Dopamine isn’t the enemy—low brain energy is. When your mitochondria can’t make enough ATP, your neurons misfire, leading to fatigue, brain fog, and lack of focus. In this video, I explain why dopamine problems are really energy problems, how mitochondrial health drives motivation and clarity, and why creatine is one of the most effective and affordable nootropics for restoring mental performance. Learn the biohacks that protect your brain’s power plants and keep you sharp all day long. Chapters 0:00 – Introduction 0:22 – Brain energy vs dopamine 0:49 – ATP shortage causes fatigue 1:53 – Prefrontal cortex and energy 3:08 – Why ATP fuels focus and mood 4:40 – Stress, sleep and mitochondria 6:00 – Biohacks for energy production 7:39 – Backup battery: phosphagen system 8:46 – Creatine for brain energy & focus 13:18 – Vegans, women and creatine needs 15:07 – Best practices for dosing creatine 17:53 – Daily creatine + electrolytes Connect with Dave Asprey! Website: https://daveasprey.com TikTok: / daveaspreyofficial Instagram: / dave.asprey Facebook: / daveaspreyofficial X: https://x.com/daveasprey YouTube: / daveaspreybpr The Human Upgrade Podcast: / thehumanupgradepodcast / thehumanupgrade Danger Coffee: https://dangercoffee.com/DAVE15 Dave Asprey’s BEYOND Conference: https://beyondconference.com/ Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-medita... Dave's favorite supplements: https://www.shopsuppgradelabs.com/dis... Upgrade Collective: https://www.ourupgradecollective.com Upgrade Labs: https://upgradelabs.com 40 Years of Zen: https://40yearsofzen.com