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MAOIs, Tyramine and Hypertensive Crisis. Treatment Considerations with monoamine oxidase inhibitors скачать в хорошем качестве

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MAOIs, Tyramine and Hypertensive Crisis. Treatment Considerations with monoamine oxidase inhibitors
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MAOIs, Tyramine and Hypertensive Crisis. Treatment Considerations with monoamine oxidase inhibitors

Dr. Pagnani of Rittenhouse Psychiatric Associates discusses monoamine oxidase inhibitors (MAIOs), their mechanism of action, their role in treating depression and possible side effects. Monoamine oxidase inhibitors (MAOIs) prevent the oxidation (breakdown) of monoamines like serotonin, dopamine and norepinephrine in the central nervous system. This can result in the effective treatment of depression, and a trial may be warranted, particularly if an individual has failed more common treatment modalities. With that said, MAOIs carry a great deal of potential side effects, and one in particular (from the ingestion of foods high in tyramine) can result a serious / possibly deadly medical condition called a hypertensive crisis. This can occur as MAOIs prevent the breakdown of tyramine and tyramine can regulate blood pressure. Individuals taking MAOIs need to be under the direct supervision of a medical provider, and they also must be educated on keeping a low tyramine diet (avoiding foods such as [but not limited to] aged cheese, cured meats, fava beans, chianti, draft beer, pickled/ fermented foods, processed and tenderized meats, dried or overripe fruits, yeast extract spreads, various sauces (like soy sauce), brewer's yeast, and sour dough bread. Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations. Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly. These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step. Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen. This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE. If you are researching a specific topic, please view our Youtube channel, click all videos and use the search function. Please also visit and follow us on instagram and FB: @RittenhousePsych. www.RittenhousePA.com www.ChrisPagnaniMD.com

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