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Get An Introductory Guide to Longevity and my weekly newsletter here (free): https://bit.ly/3Y4k2xj Watch the full episode: • 345 ‒ Chronic pain: pathways, treatment, a... Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode #345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D. In this clip, they discuss: How NSAIDs Work – A clear explanation of COX enzymes, prostaglandins, and how NSAIDs reduce inflammation and pain NSAIDs vs. Steroids – Understanding the difference in mechanism and why it matters clinically Side Effects & Risk Management – Exploring GI bleeding, kidney function, cardiovascular events, and how to lower the risk Why Dose and Duration Matter – How even short courses of NSAIDs can carry significant risk depending on patient profile -Choosing the Right Anti-Inflammatory – When to use (or avoid) NSAIDs and how to individualize treatment safely -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/