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Intracameral nonpreserved lidocaine 1% with 1 minim of 10% phenylepherine at the beginning of phacoemulsification cataract extraction and Intracameral and Intracorneal Vigamox ®150µg / 0.1 cc (dilution: 3 parts Vigamox + 7 parts BSS) at the end. This preparation method of the moxifloxacin was given to me by Dr. STEVE ARSHINOFF, and here is what he sent me. Intracameral Vigamox ® in Jan. 1, 2016. Supplied: Alcon Laboratories: Vigamox® (moxifloxacin (Alcon) 0.5% eye drops = 500µg / 0.1 cc. Goal: 150µg / 0.1 cc (dilution: 3 parts Vigamox + 7 parts BSS) To get 150 µg / 0.1 cc: Simply dilute eye drops to 30% concentration of supplied Vigamox® Method: Inject 0.3 cc of Vigamox® 150 µg / 0.1 cc at the end of each case = 450 µg. ! 1.5 mg/ml in AC (Essentially, this is an exchange of the entire AC volume with the Vigamox ® solution) To make up 150 µg / 0.1 cc Vigamox: 1. 3 ml Vigamox® withdrawn into 10 or 12 cc syringe with sterile needle, from new Vigamox® bottle. 2. 7 ml BSS drawn into same syringe, from a new 15 cc BSS bottle (mixed by the turbulence of aspiration). - 0.5 cc injected into medicine cup on surgical tray by circulating nurse. 3. Scrub nurse draws up the Vigamox solution into a TB syringe to hand to surgeon. 4. Surgeon injects ~0.3cc through the side port as the last step of surgery, under the distal capsulorhexis edge (1) and then exiting the eye, with a final spurt of injection at the incision (2), making sure the AC is left pressurized. This is a planned exchange of the entire AC contents, and is therefore very easy to do. Thanks to Dr. Steve Arshinoff MD FRCSC