Tubulosquamous polyps; Benign polyp made up of squamous epithelium and glandular tubules скачать в хорошем качестве

Tubulosquamous polyps; Benign polyp made up of squamous epithelium and glandular tubules

Tubulosquamous polyps are rare, benign vaginal lesions composed of squamous epithelium and tubular glandular elements within a fibrous stroma. They are thought to originate from misplaced periurethral Skene glands and are usually treated with simple local excision. 🧬 Definition & Origin Histology: Mixture of squamous epithelium and small tubular structures embedded in a collagenous (fibrous) stroma. Origin theory: Believed to arise from misplaced periurethral Skene glands (female paraurethral glands). Nature: Benign, non-cancerous lesion. 📍 Epidemiology & Sites Rarity: Very uncommon, only a small number of cases reported. Age range: Typically seen in women aged 39–78 years, often postmenopausal. Location: Most commonly found in the upper vagina, but can occur anywhere in the vaginal wall. 🔎 Clinical Features Presentation: Often discovered incidentally during pelvic exams. May present as a polyp or cyst. Some cases associated with postmenopausal bleeding. Size: Usually small, up to 3 cm in diameter. Macroscopy: Solid cut surface, polypoid appearance. 🧪 Microscopic Characteristics Squamous component: Glycogenated, eosinophilic or clear cells; nests may contain keratinous debris. Tubular component: Small tubules lined by cuboidal cells, sometimes forming micropapillary projections. Stroma: Hypocellular fibrous tissue. Surface: Covered by squamous epithelium, occasionally keratinized. 💊 Management & Outcome Treatment: Simple local excision is curative. Prognosis: Excellent; lesions are benign with no known malignant potential. Follow-up: Usually not required beyond routine gynecological care. ⚠️ Key Considerations Differential diagnosis: Must be distinguished from other vaginal polyps, cysts, or rare neoplasms. Clinical importance: While benign, recognition is important to avoid misdiagnosis as malignant lesions. #Polyps