Human Placenta in 3D with SMA, HLA-G, and CD31 Staining скачать в хорошем качестве

Human Placenta in 3D with SMA, HLA-G, and CD31 Staining

SMA, HLA-G, and CD31 staining reveal smooth muscle, trophoblasts, and vasculature — from whole-tissue scans to single-cell resolution with HOTLS microscopy. This 3D dataset captures the intricate architecture of the human placenta, imaged with the Aurora™ 3Di Hybrid Open Top Light Sheet (HOTLS) microscope. The video begins with individual fluorescence channels, then builds to a composite view, highlighting tissue complexity in vivid detail. Stains used: 🟣 SMA (Purple): smooth muscle structures 💛 HLA-G (Yellow): placental trophoblast cells 🌐 CD31 (Cyan): vascular endothelium The workflow demonstrates seamless transitions from low-resolution Scout scans to high-resolution Zoom imaging, reaching single-cell resolution. At 00:47, the dataset zooms into detailed cellular features within the placenta’s structural framework. By combining 3Dm data management and 3Dai AI-powered segmentation, this dataset enables quantitative analysis of: Trophoblast organization Vascular architecture Immune interactions Applications include: Reproductive biology Placental health research Maternal–fetal medicine, where understanding cellular and vascular networks is essential This example shows how 3D histology delivers intact, multi-scale insights that 2D methods cannot capture. https://www.alpenglowbiosciences.com/...