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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,[email protected], https://plus.google.com/communities/1... , ,https://plus.google.com/u/0/+Alexandr... , / @otolaryngologistorlent-med3259 , / @alexandrosg.sfakianakis4746 , https://twitter.com/g_orl?lang=el, / alexandrossfakianakis , Impact of bone volume upon condylar activity in patients with unilateral condylar hyperplasia via Oral and Maxillofacial Surgery Publication date: Available online 28 March 2018 Source:Journal of Oral and Maxillofacial Surgery Author(s): Luc H.E. Karssemakers, Jitske W. Nolte, D.Bram Tuinzing, Geerling E.J. Langenbach, Alfred G. Becking, Pieter G. Raijmakers PurposeUnilateral condylar hyperplasia/ hyperactivity (UCH) is a bone overgrowth disorder affecting the mandible. The purpose of this study is to determine the relationships between age, condylar bone structure, condylar bone volume and condylar bone activity on SPECT scans in UCH patients.MethodsThis study included 20 patients with a clinical presentation of progressive mandibular asymmetry and a positive bone SPECT scan. A bone SPECT derived standardized uptake value (bSUV) for the condylar region was determined. All patients underwent condylectomy to arrest further progression of the disease. The resected condyles were scanned with a microCT scanner (18 μm resolution). Bone architectural parameters were calculated with routine morphometric software.ResultsThe mean bSUV of the condyle on the affected side was 15.32 (SD ±8,98) compared to 9.85 (SD ±4.40) on the non-affected side (p=0.0007). For the trabecular bone structure there was a non-significant correlation between the SUV of the affected condyle and the measured bone volume fraction (r=0.13, p=0.58), trabecular thickness (r=0.03, p=0.90).ConclusionNo significant relation was found between condylar bone volume fraction and the condylar activity in a bone scan; therefore, the impact of bone volume fraction on the results of bone scans is limited. The measured condylar activity on the SPECT scan seems primarily a reflection of the remodeling rate of bone. Add tags (Currently: Cranio-Maxillofacial Surgery, Medicine by Alexandros G. Sfakianakis)