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Atypical Parkinsonisms present with some of the signs and symptoms of Parkinson’s disease, but generally do not respond well to drug treatment with levodopa. Yvette Bordelon received her MD and PhD degrees from the University of Pennsylvania. Her thesis work was performed with Dr. Marie-Francoise Chesselet and focused on understanding the brain circuitry involved in movement and mood and thinking. She went on to residency training at Massachusetts General and Brigham and Women’s Hospitals and then did a Movement Disorders Fellowship at Columbia University. Dr. Bordelon specializes in atypical variants of Parkinson’s disease, and in 2024 joined the Movement Disorders Program in the Department of Neurology at Cedars Sinai. A Parkinson's Community Los Angeles (PCLA) "Let's Talk Parkinson's" online live program from July 12, 2024. www.pcla.org. ----------------------------------------------------------------------------------------------------------------------- Timestamps: 00:00 Intro 01:09 Speaker Intro 03:00 Outline 03:15 Overview of Atypical Parkinsonisms 03:46 Diagnosis 04:50 Parkinsonisms plus… 06:43 Diagnosis continued 08:54 Is an exact diagnosis necessary to guide treatment? 09:48 Classified by Pathologic Cause 11:29 Location of protein tangles - relates to symptoms 13:07 TAU Disorders 13:19 Progressive Supranuclear Palsy (PSP) 20:27 Corticobasal Degeneration/Syndrome (CBD/S) 23:40 Synuclein Disorders 23:48 Multiple System Atrophy (MSA) 27:31 Dementia with Lewy Bodies (DLB) 30:39 Other Parkinsonisms 31:12 Summary of Parkinsonism Diagnosis 34:48 Atypical Parkinsonism Treatment 40:18 Why exercise? 40:56 Research pipeline: treatments under development 41:15 Tauopathies 41:53 PSP Clinical Trial: Enrolling 42:48 Synucleinopathies 44:11 Trial for all atypical Parkinsonisms 46:52 Multi-Disciplinary Holistic Care 47:54 Summary 49:09 Q&A 56:52 Closing ----------------------------------------------------------------------------------------------------------------------- 🎥 Related Content: Let's Talk Parkinson's Online Events Playlist: • "Let's Talk Parkinson's" Online Events Connect with PCLA: 👉 Website: www.pcla.org 👉 PCLA Blog: https://pcla.org/blog/ 👉 Instagram: / parkinsons.la 👉 Facebook: / parkinsonscommunityla 👉 Twitter: / pdcommunityla Parkinson's Community Los Angeles is a non-profit organization. If you enjoyed this free program, please consider donating to PCLA on our website at https://pcla.org/donate/. PCLA's online events are intended as an informational and educational resource for the Parkinson's community. Always consult with your healthcare team for medical and treatment advice. The views and opinions expressed by presenters and participants do not necessarily reflect those of PCLA. Sponsorship support does not influence PCLA's content perspective or panelist selection. #parkinsons #parkinsonsdisease #pcla