Collagenase II: Precision in Tissue Engineering | GlpBio скачать в хорошем качестве

Collagenase II: Precision in Tissue Engineering | GlpBio

Collagenase Ⅱ is an enzyme that belongs to the class of proteolytic enzymes known as collagenases. It is produced by certain bacteria, such as Clostridium histolyticum, and is widely used in various biomedical and biotechnological applications. Collagenase Ⅱ specifically targets and breaks down collagen, which is the main structural protein in connective tissues such as skin, tendons, and bones. This enzyme is able to cleave the peptide bonds in the collagen molecule, leading to its degradation and breakdown into smaller fragments. In biomedical research and clinical applications, collagenase Ⅱ is commonly used in tissue dissociation and cell isolation procedures. It is particularly useful for breaking down the extracellular matrix in tissues, allowing for the isolation of specific cell types for further study or therapeutic purposes. In addition to its role in cell isolation, collagenase Ⅱ is also used in the production of collagen-based biomaterials and in the treatment of conditions such as Dupuytren's contracture and Peyronie's disease, where excessive collagen deposition leads to tissue contracture and fibrosis. Overall, collagenase Ⅱ is a valuable enzyme with diverse applications in biomedical research, biotechnology, and clinical medicine, due to its ability to specifically target and degrade collagen, the most abundant protein in the human body. For details please check: https://www.glpbio.com/collagenase.html