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Post-SSRI Sexual Dysfunction (PSSD) is a condition that has puzzled many in the medical community. For numerous patients, it is a devastating reality that severely affects their quality of life. In this video, Dr. Sanil Rege, a consultant psychiatrist, delves into the complexities of PSSD, drawing insights from Post-Finasteride Syndrome (PFS), another condition known for persistent sexual dysfunction even after medication cessation. We will explore the pathophysiology, diagnosis, and potential treatment avenues for PSSD. Dr. Rege discusses the overlapping mechanisms between PSSD and PFS, including the role of neuroactive steroids, androgen receptors, gene expression changes, and the gut-brain axis. By examining these commonalities, we aim to shed light on potential treatment strategies that could provide relief to those suffering from these conditions. The video covers a range of important topics, from the impact of serotonergic inhibition on dopamine release to the role of epigenetic modifications and endocrine abnormalities. Additionally, we discuss how alterations in the gut microbiome can influence sexual behaviour and mood, linking gut health to PSSD and PFS symptoms. Join us as we tackle this critical topic and strive to understand more about these debilitating conditions. Don't forget to stay until the end of the video, where we explore potential treatment options and emerging research that could offer hope to those affected by PSSD and PFS. From neuroactive steroid therapy to modulation of the gut microbiome and dopamine agonists, we delve into the most promising avenues for future research and treatment development. Welcome to Psychiatry Simplified! If you're passionate about neuroscience, psychiatry, and mental health, hit the subscribe button to stay updated with our latest releases. Check out our other videos for more in-depth discussions on related topics. Your support and comments are invaluable to us, and we look forward to learning together. #PSSD #PostSSRISexualDysfunction #PFS #PostFinasterideSyndrome #MentalHealth #PsychiatrySimplified #DrSanilRege #Neuroscience #SexualDysfunction #Psychiatry #GutBrainAxis #Neurosteroids #MentalHealthAwareness #SSRI #Finasteride #Propecia #Proscar #Dutasteride #Avodart #Dopamine #NeuroactiveSteroids Relevant Resources: 👉Psychiatry Training : https://www.academy.psychscene.com Related Videos 👉What is POST-SSRI SEXUAL DYSFUNCTION| PSSD | Antidepressants and Persistent Sexual Dysfunction • What is POST-SSRI SEXUAL DYSFUNCTION|... 👉SSRIs and Emotional Blunting | Mechanisms of Emotional Blunting and Treatment • SSRIs and Emotional Blunting | Mechan... 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is devoted to making you a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: / psychscenehub Instagram: / psychiatry.excellence – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: / sanilrege