2025 Breast Cancer Immunotherapy Trials: Key Updates from Dr. LeVee | MOASC/ANCO скачать в хорошем качестве

2025 Breast Cancer Immunotherapy Trials: Key Updates from Dr. LeVee | MOASC/ANCO

ARTICLE: https://oncologytube.com/breast-cance... Join Dr. Alexis LeVee, MD, Clinical Instructor of Medicine at UCLA David Geffen School of Medicine, as she presents groundbreaking 2025 updates on breast cancer immunotherapy trials at the MOASC/ANCO Immuno-Oncology Symposium: Emerging Data & Evolving Paradigms (September 6, 2025). From de-escalating neoadjuvant therapy in early TNBC to novel combinations in metastatic settings, discover how trials like KEYNOTE-522, neoPACT, NeoSTAR, BELLINI, and ASCENT-04 are reshaping treatment paradigms for oncologists and patients. Highlights include: Chemo-sparing strategies with dual ICIs achieving up to 47% pCR in high-TIL TNBC (BELLINI trial). Anthracycline-free regimens hitting 58% pCR (neoPACT). SG + pembrolizumab boosting PFS to 11.2 months in advanced TNBC (ASCENT-04). Ideal for oncology professionals seeking actionable insights on biomarkers, ADCs, and emerging compounds. Full slides and resources available at moasc.org and anco.org. Timestamps: 0:00 - Opening Teaser: BELLINI & ASCENT-04 Highlights 0:30 - Dr. LeVee's MOASC Young Investigator Award & Gut Microbiome Project 1:15 - KEYNOTE-522: Pembrolizumab Approval in Early TNBC 2:30 - neoPACT Trial: Anthracycline-Free Regimen (58% pCR) 3:45 - NeoSTAR Trial: SG + Pembrolizumab (33-50% pCR) 5:00 - BELLINI Trial: Dual ICI Without Chemo (33-47% pCR) 6:15 - Adjuvant De-Escalation: OptimICE-pCR & OPT-PEMBRO 7:30 - Adjuvant Escalation for Residual Disease: ASCENT-05, TROPION-Breast03 8:45 - Metastatic TNBC: ASCENT-04 Results (11.2 mo PFS) 10:00 - Novel Strategies: Ivonescimab, Bispecifics, & Cellular Therapies 11:15 - Biomarkers: TILs, MammaPrint, & ImPrint Signatures 12:30 - Q&A & Closing: Future Directions Subscribe for more oncology updates from leading experts! #BreastCancerTrials #Immunotherapy Presented by UCLA Health | Jonsson Comprehensive Cancer Center. (Recorded September 6, 2025) Video interviews to be posted from this event at these websites... https://oncologytube.com/tag/moasc/ https://moasc.org/ https://anco.org/ About OncologyTube.com: OncologyTube.com is a free video-sharing platform dedicated to oncology professionals, offering cancer research updates through videos, audio, PowerPoint presentations, and more. Visit OncologyTube.com for a detailed web post on this and many other cancer topics and oncology insights. Follow OncologyTube: eNewsletter: https://oncologytube.com/newsletter/ Twitter:   / oncologytube   LinkedIn:   / oncologytube-com   Facebook:   / oncologytube   Instagram:   / oncologytube   YouTube:    / oncologytube   Connect with Us: Share your thoughts in the comments! Join the discussion.