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Anosmia is the inability to smell. Some people haveTrusted Source anosmia from birth, whereas others lose their ability to smell over time. Experts suggest that anosmia and hyposmia affect about 3–20%Trusted Source of the population. Hyposmia is a decreased ability to smell. Sometimes people call anosmia smell blindness. The condition may be permanent or temporary. Smell is a complex process that involvesTrusted Source communication between the brain and nose. When a person sniffs an odor, air travels into the nose, and the odor molecules attach to receptors on the nerve that sense smell, called the olfactory nerve. These nerves line the olfactory epithelium, which is the tissue lining the nasal cavity. When odor molecules from the environment stimulate these nerves, they transmit signals to the brain. The brain receives the olfactory information and processes it into a scent that a person can identify. Signs and symptoms When people develop anosmia, they may notice that they can no longer smell identifiable odors. On the other hand, people who were born with anosmia due to genetic differences may not recognize they have anosmia, because they never had the ability to smell. Neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease, may causeTrusted Source a loss of the sense of smell. If people living with neurodegenerative diseases recognize a loss of the sense of smell, they should seek medical evaluation as soon as possible. Sometimes anosmia is the earliest sign of neurodegenerative diseases. When a person can no longer smell, they are unable to sense warning odors in foods and the environment. People living with anosmia may experience a lower quality of life related to social interactions, eating, and feelings of well-being.