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This video provides a practical overview of how ROTEM (Rotational Thromboelastometry) can be applied in patients with liver disease and during liver transplantation. Topics covered include: Key changes in hemostasis seen in liver disease and why conventional tests often fall short. How to perform and interpret ROTEM assays such as EXTEM (extrinsic pathway and clot dynamics) and FIBTEM (fibrin-based clot stability). The strengths of ROTEM, including rapid bedside assessment and the ability to distinguish bleeding risk, hypercoagulability, and fibrinolysis. Important limitations, such as technical expertise requirements and insensitivity to certain platelet or von Willebrand factor defects. A step-by-step look at ROTEM-guided transfusion strategies—how to use results to guide targeted therapy with fibrinogen concentrate, platelets, PCC, or antifibrinolytics, instead of empirical plasma transfusion. Recognition and treatment approaches for hyperfibrinolysis in the perioperative setting. This session is intended for anesthesiologists, transplant teams, intensivists, and anyone involved in perioperative coagulation management. It highlights how ROTEM can improve both patient safety and blood product stewardship in liver transplantation. #ROTEM #LiverTransplantation #Hemostasis #CoagulationMonitoring #EXTEM #FIBTEM #PointOfCareTesting #Hyperfibrinolysis #BloodManagement #LiverDiseaseCare #PerioperativeMedicine #rebalanced #rebalancedcoagulation