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This video teaches you about Hyperosmolar Hyperglycemic Nonketotic Syndrome that in severe cases can lead to #alteredmentalstatus eventually resulting in coma. Hyperosmolar Hyperglycemic Nonketotic Syndrome is a Life-threatening Medical Emergency that is commonly seen in older patients with Type 2 Diabetes Mellitus that have restricted fluid intake Relatively low insulin levels favors glucagon's function Glucagon then functions in the liver to increase glucose production, increase glycogenolysis and decrease utilization of glucose All of this raises the total Blood Glucose Levels Now, This problem worsens when the patient is not consuming enough fluids throughout his/her day because restricting fluid intake in addition to hyperglycemia further increases the osmolarity of the blood hence the name of the disease Hyperosmolar Hyperglycemia State None or minimal ketone bodies are formed as some amount of insulin is still present preventing ketoacidosis hence differentiating the disease from Diabetic Ketoacidosis Symptoms Include: Glycosuria: Glucose gets filtered out by the kidneys into the urine Dehydration: On its way into the urine, Glucose pulls water with it as glucose is an osmotic agent which further reduces the total bodily fluid In the CNS, Hyperosmolarity in the blood stream pulls water out of CNS causing Altered Mental Status which can progress to coma in severe cases Figures in this video were made by using images from Servier Medical Art (http://smart.servier.com/), licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/...) If you found this video helpful, please like and share with your friends And also make sure to subscribe to our channel and turn on the bell icon so you do not miss any future videos from us ------------------------------------------------------------------------------------------------------------------------ SUPPORT (EVERY DOLLAR WILL HELP THE CHANNEL GROW): http://paypal.me/panmedicad Subscribe to Panmedicad: / @panmedicad Follow on: FACEBOOK: / panmedicad INSTAGRAM: / panmedicad #hyperosmolarhyperglycemicnonketoticsyndrome #alteredmentalstatus #hypoglycemia ----------------------------------------------------------------------------------------------- Intro by: VipexArtz Music: Symbolism - Electrolight Logo By: Gerd Altmann