Anaplastic carcinoma of thyroid : Pathology USMLE Step 1 скачать в хорошем качестве

Anaplastic carcinoma of thyroid : Pathology USMLE Step 1

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash Anaplastic carcinoma of thyroid : Pathology USMLE Step 1 Anaplastic carcinoma of the thyroid is an aggressive and rare type of thyroid cancer that accounts for less than 5% of all thyroid malignancies. It typically occurs in older individuals and has a poor prognosis due to its aggressive behavior and resistance to treatment. Pathologically, anaplastic carcinoma of the thyroid is characterized by the presence of large, pleomorphic cells with frequent mitotic figures and areas of necrosis. The tumor cells have lost their normal thyroid cell characteristics and are no longer responsive to thyroid-stimulating hormone (TSH). Immunohistochemical studies of anaplastic carcinoma of the thyroid may show expression of epithelial markers such as cytokeratin and epithelial membrane antigen (EMA), as well as markers of mesenchymal differentiation such as vimentin and smooth muscle actin. Genetic alterations, including mutations in TP53, BRAF, and RAS genes, are commonly associated with anaplastic carcinoma of the thyroid. These mutations are thought to contribute to the aggressive nature of the tumor by promoting uncontrolled cell proliferation and inhibiting apoptosis. Treatment for anaplastic carcinoma of the thyroid typically involves surgical resection, although the extent of resection depends on the size and location of the tumor. Radiation therapy and chemotherapy may also be used to help control the disease, although their effectiveness is limited due to the tumor's aggressive nature. #pathology #pathologyusmle #pathologylab #neetpgpathology #fmgepathology #usmlepathology #fmge #fmgevideos #rapidrevisionfmge #fmgejan2023 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2023 #usmleprep