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Join Toba Isaac Olatoye, a master's degree holder from the University of Ilorin, as he presents his published research on natural inhibitors of cholesterol biosynthesis. His work uses computational molecular docking to evaluate phytochemicals from the medicinal plants Cochlospermum planchonii and Cochlospermum tinctorium. Toba explains how these compounds could offer a natural solution to managing high cholesterol, potentially providing a safer alternative to long-term statin use. This video was recorded by the author. Read the full article here: https://xbio.jmir.org/2025/1/e71675 #NaturalMedicine #Cholesterol #DrugDiscovery #Phytochemicals #MolecularDocking #MedicinalPlants #CardiovascularHealth #Statins #UniversityOfIlorin #BiochemistryResearch Please cite as: Olatoye T Discovery of Novel Inhibitors of HMG-CoA Reductase Using Bioactive Compounds Isolated From Cochlospermum Species Through Computational Methods: Virtual Screening and Algorithm Validation Study JMIRx Bio 2025;3:e71675 URL: https://xbio.jmir.org/2025/1/e71675 DOI: 10.2196/71675 ### About JMIR Publications JMIR Publications is a leading open access publisher of digital health research and a champion of open science. With a focus on author advocacy and research amplification, JMIR Publications partners with researchers to advance their careers and maximize the impact of their work. As a technology organization with publishing at its core, we provide innovative tools and resources that go beyond traditional publishing, supporting researchers at every step of the dissemination process. Our portfolio features a range of peer-reviewed journals, including the renowned Journal of Medical Internet Research. To learn more about JMIR Publications, please visit https://www.JMIRPublications.com or connect with us via: YouTube - / jmirpublications Facebook - / jmedinternetres X - https://x.com/jmirpub BlueSky - https://bsky.app/profile/jmirpub.bsky... LinkedIn - / jmir-publications Instagram - / jmirpub Head Office - 130 Queens Quay East, Unit 1100 Toronto, ON, M5A 0P6 Canada Media Contact - Communications@JMIR.org The content of this communication is licensed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/..., which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, published by JMIR Publications, is properly cited.