NEVELIA - Dermal Regeneration Process скачать в хорошем качестве

NEVELIA - Dermal Regeneration Process

SYMATESE is introducing NEVELIA® Bi-Layer Matrix which is a sterile medical device consisting of a collagen layer to promote dermal regeneration and a reinforced silicone layer acting as a pseudo-epidermis The type I, purified, stabilised, bovine origin collagen is supplied as a porous matrix. This matrix serves as a support for cell infiltration, thus contributes to the natural tissue regeneration process. It is resorbed, becoming a vascularised tissue that is histologically very close to the normal dermis, from 2 to 3 weeks after it is implanted. NEVELIA® Bi-Layer Matrix is manufactured, and packaged under ISO 13485 quality standards applicable to medical devices. Quality controls are performed at all stages of the production. The NEVELIA® Bi-Layer Matrix is sterilized by radiation. NEVELIA® Bi-Layer Matrix is indicated for dermal regeneration in individuals with skin loss, particularly in the following fields: • Burns surgery (third and deep second degree burns) • Reconstructive plastic surgery • Traumatology NEVELIA® Bi-Layer Matrix is used in combination with a thin split thickness skin graft (STSG) to recreate skin resembling normal skin in terms of function and appearance. NEVELIA® Bi-Layer Matrix is particularly useful for: Patients who are unable to supply sufficient donor skin for an autograft at the time of excision When the physiological condition of the patient does not allow the autograft DERMAL REGENERATION PROCESS Day 0 Contracted Scar The surgery can be scheduled as soon as the patient is stabilized Day 1 Excision of the Wound All the dead tissue on and around the graft zone must be removed. For the success of NEVELIA® Bi-Layer Matrix, all necrotic and scar tissues must be excised down to the viable tissue Day 1 NEVELIA® Bi-Layer Matrix Application NEVELIA® Bi-Layer Matrix must be cut to fit the excised wound size exactly The collagen matrix must be in direct contact with the excised wound. The matrix will be fixed in place with surgical staples or sutures Day 1 to 21 Neoderm Formation The collagen matrix is quickly colonized by the patient’s cells and is gradually replaced by an autologous neoderm Day 21+ Removal of the Silicone Layer When the neoderm is formed, the silicone layer is removed. The reconstructed dermis has a distinctive orange-yellow or light yellow colour and may present with slightly reddish areas, sign of a good revascularization Day 21+ Harvesting of the Graft A thin split thickness skin graft must be taken, if possible from an area similar in colour to the reconstructed area. It must be removed with a dermatome and may be meshed Day 21+ Thin Split Thickness Skin Graft The graft is placed on the neoderm and it is fixed with staples or suture Day 45+ Regenerated Skin Epidermization Complete healing of the wound