Genetic Basis For Production Of THCV, A Rare And Potentially Medically Valuable Cannabinoid скачать в хорошем качестве

Genetic Basis For Production Of THCV, A Rare And Potentially Medically Valuable Cannabinoid

Tags: THCV, rare cannabinoids, markers, breeding, cultivation, varin, genetics Alisha Holloway, PhD presents "Genetic Basis For Production Of THCV, A Rare And Potentially Medically Valuable Cannabinoid" at CannMed 2022. 0:00 Intro 1:42 What is THCV? 3:04 Medical Potential of THCV 5:04 Medical Application 6:16 Recreational Application 7:06 THCV is rare 8:28 Different Starter Molecules, Same Enzymes 12:16 Marker-Assisted Breeding 13:12 Discovery of Genetic Markers 14:30 Mapping of Total Varin Markers 17:20 KR Gene 18:28 Mapping Total Varin in Germplasm with KR Marker 19:29 Deployment of Markers in Breeding Program 20:24 Next Steps and Conclusions 21:52 Acknowledgements 23:31 Q&A Tetrahydrocannabivarin (THCV) is a rare cannabinoid that has medical potential as a neuroprotectant, anti-inflammatory, and most notably as a therapeutic to improve glycemic control in type 2 diabetic patients. THCV has been found at low levels in some cannabis plants. We sought to understand the genes involved in the pathway for production of cannabinoids like THCV and to develop genetic markers for breeding plants with high levels of THCV. The KR gene is a strong candidate for influencing THCV production. We found five additional genomic regions which, in combination with the KR-associated markers, explain variation in THCV cannabinoid production. We implemented these genetic markers in marker-assisted breeding to develop high THCV cultivars.