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Presented By: Elizabeth Delery, PhD - Postdoctoral Fellow Department of Physiology, Louisiana State University Health Sciences Center Speaker Biography: My passion for science started at a very young age. My dad was a forensics investigator for the New Orleans police department & after school I would spend time in the lab where he taught me about DNA, fingerprints, & microscopy. I was fascinated by the puzzle of all of it and I made my life goal to be an "ist" (scientist, biologist, paleontologist, etc.). My teachers & professors encouraged my love of science & made sure to emphasize the contributions of women in science, like Marie Curie, Rosalind Franklin, & Barbara McClintock. I admired the sacrifices these women made in order to help humanity & advance their fields. Webinar: Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model Webinar Abstract: The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricles, produces cerebrospinal fluid, and protects the brain via a physical barrier. Perivascular macrophages line the stromal capillaries through it, and tight junctions between the apical sides of the epithelial cells regulate the microenvironment. The choroid plexus is also believed to be an immune interface between peripheral and CNS immune systems and plays a major role in the resolution of neuroinflammation by recruiting monocytes and leukocytes into the CNS. It has also been proposed to be a target of viral infection, such as a human immunodeficiency virus (HIV) reservoir, and a site of damage in cerebral hemorrhage, stroke, and hypoxia. Since the choroid plexus can allow transmigration of leukocytes, recruit myeloid cells, control diffusion of small molecules and water, and control drug permeability into the CSF, it is important to have an ex-vivo culture model. Earn PACE Credits: 1. Make sure you’re a registered member of LabRoots (https://www.labroots.com/ms/webinar/c...) 2. Watch the webinar on YouTube or on the LabRoots Website (https://www.labroots.com/ms/webinar/c...) 3. Click Here to get your PACE credits (Expiration date – July 31, 2021 09:00 AM): https://www.labroots.com/credit/pace-... LabRoots on Social: Facebook: / labrootsinc Twitter: / labroots LinkedIn: / labroots Instagram: / labrootsinc Pinterest: / labroots SnapChat: labroots_inc