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You may know that yeast is used to make bread, beer, wine, and other fermented foods and beverages. But what you may not know is that yeast has been also used as a model organism in scientific research for decades because, surprisingly, yeast and humans share a lot of similarities. Yeast can be used for a wide range of applications, such sustainable drug production, production of biofuel or novel biomaterials, or for diagnostic purposes. With synthetic biology we aspire to being able to program biology by writing DNA scripts that our chassis will execute. How can we do this with yeast cells? In this video, Alistair Elflick, Leonardo Rios and Koray Malci from the UK Center for Mammalian Synthetic Biology (University of Edinburgh) talk about yeast as a chassis in synthetic biology. This video is a part of the European Project "BioRoboost: Fostering Synthetic Biology standardisation through international collaboration". This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement N820699.