DNA rhythms orchestrate gene activity across development скачать в хорошем качестве

DNA rhythms orchestrate gene activity across development

FMI scientists discovered that thousands of genes in the worm C. elegans turn on and off in precise, rhythmic patterns during development, much like a coordinated orchestra. These gene activity rhythms occur across different tissues, ensuring every gene acts at the right moment, and are governed by chromatin— the coiled complex of DNA and proteins in a cell’s nucleus. The researchers also built a model that accurately predicts gene activity, confirming that chromatin timing directly drives developmental gene rhythms, offering insights into biological clocks in people.