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Ever wonder what it is like to get your lips reversed after your filler has migrated? Certain dermal filler have a tendency to migrate or move from where they were first injected. The most common problem is migration of filler above the upper lip, which gives it a full appearance between the lip and the nose. Even if it has been a few years since the last injection, filler can remain in this area for an extended period and will need to be reversed to restore the natural appearance around the mouth. This video demonstrates a painless lip filler reversal with Dr. Sarah Yovino. A cannula was used to deliver the reversal agent in order to minimize bruising. The medication injected for the reversal was hyaluronadase. It is a naturally occurring enzyme in our bodies, that breaks down our own hyaluronic acid. This enzyme was manufactured and bottled to allow immediate reversal of dermal fillers, specifically hyaluronic acid fillers. The melting of the fillers is almost instantaneously seen but continues over a few hours to days. Depending on the degree of cross-linking of the fillers, the more linked the more reversal it will take to melt it away.