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Type 1 #diabetes (T1D) has long posed significant challenges for patients and researchers alike. But now, microscopic clusters of organisms are providing a glimmer of hope. Emerging as a new frontier in #T1D treatment, stem cell-derived #isletcell #therapy is a novel approach that may revolutionize the lives of patients with this chronic disease. #StemCells, with their remarkable ability to transform into specialized cells, offer the potential to restore the function of insulin-producing islet cells in the #pancreas. “The hope is that this can make a real difference by replacing damaged cells with lab-generated human islet-like #cell clusters that produce normal amounts of #insulin on demand,” said Matthias von Herrath, M.D., Scientific director of the Diabetes #Research Institute at the University of Miami Miller School of Medicine. In part two of Dr. von Herrath's episode on #InsideUMiamiMedicine, he delves into the mechanisms of protecting these islet cells from destruction by the #ImmuneSystem and the challenges associated with this #treatment, including the high costs of conducting clinical trials.