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"What Are MRI White Spots? Causes, Risk Factors, and Impact on Brain Health | Neurologist Explains" What Are MRI White Spots (Non-Specific White Matter Disease)? Mild "non-specific white spots" seen on an MRI scan are often caused by the natural aging process. These spots, also called non-specific white matter disease, may also result from small vessel disease (subcortical white matter disease). Other terms include chronic ischemic microvascular changes, microangiopathic changes, or white matter hyperintensities (leukoaraiosis). What Is White Matter? The brain's white matter contains bundles of nerve fibers, appearing white due to their myelin sheath. Small, delicate blood vessels in these areas can be blocked or damaged, reducing blood supply and causing the "white spots" seen on MRI (T2/FLAIR) or dark areas on CT scans. Severe Cases: Acute damage can lead to permanent brain cell death (infarction), known as an ischemic stroke due to small vessel disease. Chronic Cases: Slow progression may cause dementia (vascular dementia), balance issues, depression, sleep disturbances, urinary problems, or even symptoms resembling parkinsonism. Common Causes of MRI White Spots *Aging *Small Vessel Disease *High Blood Pressure, Diabetes, High Cholesterol, Obesity. For context, 41.9% of U.S. adults were obese as of 2017 (CDC Data). *Smoking *Head Trauma *Migraine (Possible Association) Less Common Causes: *Autoimmune Diseases: e.g., Multiple Sclerosis *Brain Infections *Rare Genetic Disorders Learn More About Managing Risk Factors Check out “My Cholesterol Guide” by the American Heart Association (Download Here). About GEM Neurology At GEM Neurology in Clinton, TN, we specialize in diagnosing and managing brain health conditions like small vessel disease, vascular dementia, Parkinson’s disease, and more. Dr. Luis Zayas, a triple board-certified neurologist, internist, and former physical therapist, brings over a decade of expertise in treating movement disorders, dementia, and stroke-related conditions. GEM Neurology Services: Comprehensive neurological evaluations Expert care for white matter diseases and small vessel disease Advanced treatments for movement disorders, headaches, and epilepsy Personalized stroke management and prevention strategies Have Questions About MRI White Spots? Schedule an Appointment! If you have concerns about white spots on your MRI or other neurological symptoms, contact GEM Neurology to schedule a consultation. 📍 Location: 155 Frank L Diggs Drive, Clinton, TN 37716 📞 Phone: 865-666-4411 📅 Appointments: New patients can request an appointment by phone or email us at [email protected]. Please include your name, date of birth, contact number, and a brief reason for the visit. Visit our website for more information: https://www.gemneurology.com/ Note: New patients are approved by Dr. Zayas prior to scheduling.