The Beginner’s Guide to Cockayne Syndrome B and the ERCC6 Gene скачать в хорошем качестве

The Beginner’s Guide to Cockayne Syndrome B and the ERCC6 Gene

ERCC6 is the main pathogenic gene of Cockayne Syndrome (CS). Mutations in the CSB gene will cause cells to be unable to repair the DNA damage encountered during the transcription process, thereby causing RNA polymerase to stagnate at this position, interfering with gene expression, and ultimately causing CS disease. At present, the clinical treatment methods applied to CS can only relieve the symptoms of CS, but cannot cure the disease. Cockayne Syndrome B (CSB), also known as cockayne syndrome type ii, is related to cockayne syndrome type iii and cerebrooculofacioskeletal syndrome 1, and has symptoms including seizures, ataxia and tremor. An important gene associated with Cockayne Syndrome B is ERCC6 (ERCC Excision Repair 6, Chromatin Remodeling Factor), and among its related pathways/superpathways are DNA Double-Strand Break Repair and Transcription-Coupled Nucleotide Excision Repair (TC-NER). Affiliated tissues include eye, spinal cord and lung, and related phenotypes are intellectual disability and intrauterine growth retardation. More information and services about ERCC6 could be found in https://www.cyagen.com/us/en/communit... You can find all our services on our website: www.cyagen.com/us/en/ Follow us on Social Media: Youtube:    / cyagen   Twitter:   / cyagenbio   Linkedin:   / cyagen-biosciences   Facebook: https://www.facebook.com/profile.php?... Email： animal-service@cyagen.com (Animal Model Services) animal-bank@cyagen.com (Cyagen Catalog Models) cell-service@cyagen.com (Cell Products and Services)