Antiparkinson Drugs Made Easy: Levodopa, MAO-B, COMT, DA Agonists | MBBS Pharmacology скачать в хорошем качестве

Antiparkinson Drugs Made Easy: Levodopa, MAO-B, COMT, DA Agonists | MBBS Pharmacology

Tremor, rigidity, bradykinesia… confused about which drug does what? In this power-packed session, we’ll decode Antiparkinson Pharmacology into a crisp, exam-ready framework (with quick recall hacks). What you’ll learn ✅ • Big picture: basal ganglia circuitry, dopamine–acetylcholine balance, targets for therapy • Levodopa–Carbidopa: MOA, on–off and wearing-off, dyskinesias, nausea, orthostasis, counseling • Dopamine agonists (pramipexole, ropinirole, rotigotine, apomorphine): when to start, impulse-control AEs, sleep attacks • MAO-B inhibitors (selegiline, rasagiline, safinamide): early monotherapy, add-on for wearing-off • COMT inhibitors (entacapone, tolcapone, opicapone): levodopa prolongation, hepatotoxicity caution with tolcapone • Amantadine: NMDA effect, dyskinesia control, livedo reticularis, ankle edema, confusion • Anticholinergics (trihexyphenidyl, benztropine): tremor-predominant, drug-induced parkinsonism; avoid in elderly, glaucoma, BPH • Newer add-on: A2A antagonist (istradefylline) basics and where it fits • Special scenarios: young vs elderly, tremor-predominant vs bradykinesia-predominant, drug-induced parkinsonism • Exam must-know interactions and cautions: pyridoxine with levodopa, psychosis management, contraindications • MCQ gold: on–off vs wearing-off, ergot vs non-ergot agonists, tolcapone liver risk, amantadine skin changes Lead-Magnet CTA — Level up with 2nd Prof Buster 2.0 (Pharmacology) Unlock the full Pharmacology experience inside the MedLive app: • Complete 2nd Prof syllabus: HD lectures, color-coded notes, rapid-recall tables • Topic-wise MCQs, PYQs, and exam-pattern tests with analytics • Live doubt support, revision marathons, smart playlists for MBBS and NEET-PG/FMGE/INI-CET • Learn anywhere: mobile app with offline note-packs and progress tracking Get the MedLive by Dr Priyanka app on Google Play or Apple App Store. Enroll in “2nd Prof Buster 2.0 – Pharmacology” today and convert confusion into distinctions. #medlive #drpriyankasachdev #NEETPG #FMGE #neetpg2023 #MBBS #MedicalSchool #Doctor #NEET #NEXT #HowtostudyMBBS #2ndYearMBBS