Endocrinology | Pancreas: Overview скачать в хорошем качестве

Endocrinology | Pancreas: Overview

Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this endocrine physiology overview, Professor Zach Murphy delivers a comprehensive lecture on the pancreas, focusing on its dual hormonal regulation by insulin and glucagon. This session highlights how these two hormones function in concert to maintain glucose homeostasis, adapting to both the fed and fasting states. We begin by examining the endocrine pancreas, including the islets of Langerhans and their specialized cells—beta cells producing insulin and alpha cells producing glucagon. The lecture then explores how insulin acts during the fed state to promote glucose uptake, glycogenesis, lipogenesis, and protein synthesis, while glucagon dominates the fasting state, stimulating glycogenolysis, gluconeogenesis, and ketogenesis to elevate blood glucose levels. Through comparative analysis, we highlight the reciprocal regulation of these hormones, their second messenger pathways (tyrosine kinase for insulin and cAMP for glucagon), and their impact on target tissues like liver, muscle, and adipose tissue. You’ll also gain insight into the physiologic balance between anabolic and catabolic processes, and how disruption in this balance leads to conditions such as diabetes mellitus, insulin resistance, and glucagonoma. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media   / ninjanerdlectures     / ninjanerdlectures     / ninjanerdlectures   https://x.com/ninjanerdsci/   / ninja-nerd   💬 Join Our Community Discord:   / discord   #ninjanerd #Pancreas #PancreasOverview