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Immune thrombocytopenic purpura

These sources provide a comprehensive overview of *Immune Thrombocytopenia (ITP)**, an autoimmune bleeding disorder characterized by a reduction in platelet count, distinguishing between its presentation and management in **adults* versus *children**. The texts explain that ITP involves autoantibodies targeting platelets, leading to their destruction, and note that while children often experience an acute, rapidly resolving form, adults typically have a more **chronic, relapsing condition**. Management strategies differ significantly, with **oral corticosteroids* being the first-line treatment for both groups, although the adult-focused articles discuss various second-line treatments like *thrombopoietin receptor agonists* and *splenectomy* for refractory cases. Finally, the texts detail the *epidemiology* (e.g., ITP is more common in older females), *clinical features* (such as petechiae, purpura, and the rare risk of intracranial bleeding), and *diagnostic process* through exclusion, mainly relying on a full blood count showing isolated thrombocytopenia.