10 'Substrates', 'Inducers' and 'Inhibitors' скачать в хорошем качестве

10 'Substrates', 'Inducers' and 'Inhibitors'

Microsomal enzymes, i.e. P450 system or Cytochrome P 450, metabolize almost all drugs that enter into systemic circulation to inactive (mostly) metabolites. The drug that gets metabolized is the substrate and there are few drugs which will increase enzyme's activity and thereby increases drug metabolism, leading to decreased active drug levels in the body (known as Enzyme inducers). Similarly there are drugs which inhibit enzyme and increases drug's activity known as enzyme inhibitors. In this video I have explained various drugs that can be substrate, inducer or inhibitor and have given mnemonic to help you all remember each enzyme specific substrate, inducers and inhibitors.