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Case-control and cohort study designs are both very useful observational but analytic study designs. The fundamental difference between the two designs is the way you choose study participants. Both the designs can be applied in studies aiming at finding an association between an exposure and an outcome of interest. However, you may need to choose one for various reasons. Thumbnail: Susmita Roy #casecontrolstudy #cohortstudy #EpiMinutes .................................................................................. Let's grab the fundamental concepts of epidemiology in a few minutes. The rest is on you. You will decide how you would take them forward and apply them in real-life settings. .................................................................................. Dr Kazi Mizanur Rahman is a medical graduate (Dhaka Medical College, University of Dhaka), with post-graduate qualifications in epidemiology (MS Epidemiology, Harvard University) and population health (PhD, Australian National University). Dr Rahman worked for more than a decade at the International Centre for Diarrhoeal Disease Research, Bangladesh as a public health researcher. He also taught at James P Grant School of Public Health, BRAC University for five years. In Australia, since finishing his PhD in 2015, Kazi has been working as an epidemiologist both in academia and program with a focus on protection and promotion of health at the population level.