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Subscribe for the latest science breakdowns! And, become a member to chat 1:1 about science related topics! Here I give a quick overview of how the polio vaccines work; the inactivated polio vaccine (IPV) & the oral polio vaccine (OPV). This is of heightened importance now due to the increased detection of polioviruses in wastewater samples in the US and the UK. Adults who completed their polio vaccination but who are at increased risk of encountering poliovirus, such as traveling to a country of higher polio risk, working with the polio virus in a lab, or a healthcare worker treating patients with polio may receive one lifetime IPV booster. If an adult did not receive all recommended doses of either OPV or IPV as a child they should (and can at any time) complete their polio vaccination with IPV. Two doses of IPV provide at least 90% protection, and three doses provide at least 99% protection.