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Watch the Full Video at https://www.jove.com/v/60471/multicol.... Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery - a 2 minute Preview of the Experimental Protocol Michael Kosterhon, Meik Neufurth, Axel Neulen, Lea Schäfer, Jens Conrad, Sven R. Kantelhardt, Werner E. G. Müller, Florian Ringel University Medical Center of the Johannes Gutenberg University Mainz, Germany, Department of Neurosurgery; University Medical Center of the Johannes Gutenberg University Mainz, Germany, Institute of Physiological Chemistry; The protocol describes the fabrication of fully colored three-dimensional prints of patient-specific, anatomical skull models to be used for surgical simulation. The crucial steps of combining different imaging modalities, image segmentation, three-dimensional model extraction, and production of the prints are explained. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments