Pediatric Cancer Dependencies Accelerator скачать в хорошем качестве

Pediatric Cancer Dependencies Accelerator

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children’s Research Hospital have joined forces to drive progress against pediatric cancer. The Pediatric Cancer Dependencies Accelerator will transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into clinical trials. By combining the intellectual leadership, technical expertise and institutional resources of the three institutions, this new collaborative effort is designed to address critical gaps in knowledge related to the biological basis of childhood cancer, and how it might more effectively be treated. This project, notable for its large scale of investment, number of collaborating scientists and scientific scope, will accelerate progress in the development of new treatments for aggressive childhood cancers by: ● Developing and deploying genome editing techniques to identify hidden vulnerabilities (dependencies) in a range of high-risk childhood brain, solid and blood cancers. ● Leveraging emerging technologies to characterize the genetic and epigenetic landscape of pediatric cancers. ● Developing model systems where none currently exist for high-risk childhood cancers that have poor outcomes. ● Identifying effective combination therapies and mechanisms of drug resistance and shortening the timeline for developing new therapies. ● Developing computational approaches to mine and integrate data and develop innovative software tools for data sharing. Learn more about PedDep. https://www.stjude.org/pediatric-canc... #PediatricCancer #ChildhoodCancer #CancerResearch #PedDep #StJudeResearch #BroadInstitute #DanaFarber