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Appendicitis is the most common cause of right lower abdominal pain requiring surgery. The pain from appendicitis typically starts near the navel and shifts to the right lower abdomen, becoming sharper over time. Increased pain with coughing, movement, or jarring activities is a key indicator of appendicitis. Young people and teens are more prone to appendicitis, often due to a blockage by stool. Over 80% of appendicitis cases necessitate surgical intervention to prevent life-threatening complications like peritonitis. Diagnostic tests for appendicitis include ultrasound and CT scans, with Rovsing's sign and rebound tenderness being clinical indicators. Kidney stones are another major cause, characterized by severe pain starting from the back or side and potentially moving towards the groin. The pain from kidney stones is often described as the worst imaginable and is significantly different from that of appendicitis. Ovarian cysts, fluid-filled sacs on or in the ovaries, can cause a dull ache or sharp pain, especially upon rupture. Gastroenteritis, or stomach flu, leads to crampy, diffuse pain and is accompanied by symptoms like bloating, diarrhea, and vomiting. Irritable Bowel Syndrome (IBS) typically causes chronic discomfort and pain, not specifically in the lower right abdomen but possible. Inflammatory Bowel Disease (IBD) includes conditions like Crohn's disease, which often causes pain in the lower right abdomen. Anti-inflammatory medications are commonly used for IBD treatment, with surgery as an option in severe cases. Additional causes of lower right abdominal pain include endometriosis, pelvic floor dysfunction, ectopic pregnancy, diverticulitis, and intestinal herniation. The majority of conditions causing lower right abdominal pain require medical diagnosis and treatment, highlighting the importance of professional evaluation. Disclaimer: This information is provided for general knowledge and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor for any questions or concerns you may have about your health.